By entering a human cell, the “SARS-CoV-2” virus must bind its elevated protein to “ACE2” receptors on its surface. But you can send a taste molecule of the same shape to the virus, and it will attach to it, and then, it will fall into a trap, and will not be able to reproduce.
For their part, American scientists from the Center for Biotechnology and Interdisciplinary Research at the “Rensselaer Polytechnic Institute”, tested a similar method to neutralize dengue, zika and influenza A. Now, with colleagues from the Korea Institute for Biological Science and Biotechnology Research, they decided to test this approach on the virus New coronary.
“We are learning to prevent viral infections. We need this knowledge if we are to respond to epidemics quickly,” Ronsselaer Polytechnic Research Institute confirmed in a press release. We do not have good antivirals. To protect ourselves from future epidemics, we need an arsenal of methods that enable us to quickly adapt to emerging viruses. ”
Looking at the SARS-CoV-2 sequence data study, researchers have discovered, in the structure of the virus protein, molecules that are compatible with heparin, one of the known anticoagulants.
Scientists also tested the antiviral activity of organic materials extracted from seaweed – three types of heparin and two types of fucoidan. All five compounds are long chains of sugar molecules known as heterogeneous sugars.
The seaweed extract also significantly exceeded remicidiver, in cellular studies, a modern drug for coronavirus, in the antiviral effect. Heparin, the widely used blood thinner, played a major role in inhibiting infection. The test did not show any cellular toxicity for any of the compounds, even at the highest concentrations.