Study: Corona patients the most severe infection in the first week


A study by researchers in the United Kingdom and Italy indicates that individuals with acute respiratory syndrome 2 (CoV-2) are most likely to have the most severe infections during the first week of illness.

The systematic review and analysis of the virus found that although the virus can be prolonged among infected individuals, any living virus tends to cleanse the respiratory system within a week of the onset of symptoms.

No studies of infection with the live virus have been received after 9 days since the onset of symptoms, although patients still suffer from high loads of viral RNA.

Infection during the first week of corona

According to medRxiv *, the team says the results highlight the importance of identifying infections early and starting isolation practices as soon as symptoms appear, even when symptoms are mild.

Now, the team has conducted a study aimed at searching for viral load, viral RNA duration, corona virus in different types of samples, including those from the upper respiratory tract (URT), and researchers also compared the viral dynamics of the corona virus with those of With SARS-CoV-1 and Middle Eastern Respiratory Syndrome (MERS-CoV).

What did the study find?

After research, the team identified 79 studies on SARS-CoV-2 and eight studies on SARS-CoV-1 and 11 on MERS-CoV that met the eligibility criteria, and for -CoV-2, the average duration of viral RNA shedding was 17.2 days in Stool and 16.6 days in the serum.

Most studies evaluating the viral load -CoV-2 in the URT urine sample series showed that loads peaked within one week of symptoms appearing, before declining continuously. In contrast, SARS-CoV-1 viral loads peaked in URT samples between days 10 and 14 of the disease, and MERS-CoV viral loads peaked in days 7 to 10 of the disease.


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