Schalke suffered the second loss in the league against Werder Bremen, 1–3, after falling 0-8 against Bayern Munich last week.
“The Schalke Club has decided to relieve coach David Wagner from his duties immediately,” the club said in a statement on Sunday.
Schalke did not score any victory since returning after stopping due to Corona virus at the end of last season.
The team played 11 games, lost 9 matches and drew twice.
Since this time, Schalke 04 have only scored 5 goals, while their own has conceded 33 goals.