In a presentation during the European and International Conference on Obesity, the researchers said, “Inflammation caused by the accumulation of fatty tissue in obese people, and associated with other diseases such as type 2 diabetes and cardiovascular disease, can play a role in patients’ response to Covid-19.”
They also added that the renin-angiotensin and aldosterone system that regulates blood pressure and contains the enzyme that the emerging corona virus attaches to, may also be associated with recording more severe cases of infection, and the mentioned system can work excessively in people with obesity.
“We think that increasing fat mass may contribute to an increase in the activity of the renin-angiotensin-aldosterone system and inflammation in cases of obesity, which provides an important link between obesity, increasing the weak immune response to Covid-19 and recording worse cases in patients,” said Guess Goossens of the Dutch University of Maastricht Medical Center.
He indicated that this may be partly responsible for more severe cases of the disease in elderly people with Covid-19, and added, “Since aging is associated with changes in body composition represented by a decrease in muscle mass and an increase in fat mass, we may be led to believe that this may be. It contributes, at least in part, to the negative outcomes recorded in older individuals infected with SARS-Cove-2 virus. ”