Explains a new study published on the site by an international team of researchers medRxiv *, Details of nasal symptoms associated with loss of sense of smell and aging (loss of smell and taste) in Coronavirus disease 2019 (COVID-19), Including early symptoms, which are warning signs of infection.
These results could help control the spread of Corona by facilitating early diagnosis, and making it possible to practice effective social isolation measures earlier.
The importance of early identification of asymptomatic infection
Changes in the sense of taste and smell are thought to be present in about 80% of cases COVID-19 In Europe, this evolution is likely related to the virus’ entry into the epithelial cells carrying angiotensin II (ACE2), Including the olfactory epithelium in the upper part of the nasal cavity.
future ACE2 It is the site where the virus’s spiny protein gains entry into the host cell to start viral replication, and this development can be related to damage to the nasal and brain cells.
Reducing mucus can also cause a strange sensation in the nasal cavity, in which case this could be a precursor to a virus COVID-19 Earlier than other symptoms, the current study sought to determine whether these changes might be related to other symptoms that could explain them.
Researchers explored nasal symptoms in a group of 35 patients, including only those that could cause significant disturbances in olfactory function.
Unusual nasal symptoms
They found that nearly 70% of the patient group said they had one or more nasal symptoms, including a “strange sensation in the nose,” which is nearly 37 times more than the control group.
More than 60% said they felt abnormal dryness in the nose versus about 15% of the control group. In addition, more than half of the patient group said they felt as if a strong nasal lotion was used, while only one member of the control group reported This sensation makes the patient group 32 times more likely to have these symptoms.
In the patient group, nasal symptoms appeared mostly during the same period in which the sense of smell and taste changed, or before the latter began, and the average period of these symptoms was 12 days, on average, compared to 5 days in the control group.
Overall, about 85% and 80% of patients had problems with loss of smell and taste, respectively, which is consistent with other reports on the topic.