Why do you feel side effects after getting the second dose of the Corona vaccine?

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Dubai, United Arab Emirates (CNN) – After a long wait and some phone calls to vaccination clinics, you may have finally succeeded in getting the emerging coronavirus vaccine, which has swept the world and caused many deaths.

But, now comes the hard part, which is making sure you get your second dose on time.

Doctors were warning from the first dose and its effect on people. However, some people have reported more side effects than the second dose.

But this is not an unexpected result.

In their reports to the US Food and Drug Administration, Moderna and Pfizer said there was a marked difference in reactions to doses when they were testing their vaccines on volunteers.

“Third-degree adverse reactions were reported more frequently after the second dose than after the first dose,” Modernas statement said.

Reactions include swelling, body aches, headache and fever.

Why does this happen?

The body’s immune system alerts you when you receive the first dose, taking some precautions. However, he is more prepared upon receiving the second dose to recognize and respond to it.

“With the first dose, you have to generate an immune response from the ground up,” said Professor of Evolutionary Biology, Michael Warby, from the University of Arizona.

The body begins to produce immune cells called “B cells” to produce target antibodies. This takes some time, and is known as the ripening process.

“The second time you give someone an injection, these cells sit like a cloned army, and they can immediately start producing a very large immune response,” Wuorobi added.

Thomas Gisbert, a professor and expert in emerging viral threats at the University of Texas medical branch, notes that some vaccines may build up too much of the immune response with a single dose.

But he says the initial reinforcement strategy builds a long-term defense force.

It is reported that the flu-like symptoms that accompany any viral infection are not caused by the virus itself, but rather are caused by the body’s response.

The fever and muscle aches come from the inflammation, which in turn is a sign that immune cells, known as T cells, are sending out an alarm in the form of chemical signals called cytokines.

“You get swelling at the injection site,” Gisbert said. “People can have chills or aches and pains, or feel upset or tired.”

“These symptoms mean that your immune system is improving and the vaccine is already working,” said Dr. Rochelle Wallinsky, director of the US Centers for Disease Control and Prevention, in a White House briefing last month.

Studies indicate that immunity to the Corona virus lasts for months anyway, perhaps six months or nine months or even more.

Of course, the strength of immunity varies from person to person, there are some few cases that have been infected with Corona virus twice.

And vaccination may help speed up the process of limiting the spread of the epidemic, and perhaps provide greater protection from natural infection.

“Because all of this is happening so quickly, the main studies and data are not yet available,” Gisbert said.





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https://arabic.cnn.com/health/article/2021/02/05/coronavirus-vaccine-second-shot-effects-wellness

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