Scientists Answer: Why are the suspicions surrounding the AstraZeneca vaccine? | Health | A must for better health | DW

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Amid the controversy over Corona vaccines and the availability of sufficient quantities of them, the AstraZeneca vaccine has made headlines more than once after it was banned in several countries during the past weeks. In light of the injury of a number of those who received strokes, Germany decided Restricting the use of this vaccine to people over the age of 60 years Because of “rare but very serious side effects”.

What are the risks associated with this vaccine? What is the fate of those who were vaccinated with it? DW Arabia tried to collect these questions and searched for their answers to research and scientific institutions:

Why are certain age groups excluded from receiving the AstraZeneca vaccine again in Germany?

Experts from the Paul Ehrlich Institute, the federal authority on vaccines and medicines, said that 31 of those who received the AstraZeneca vaccine had developed what is known as cerebral venous sinus thrombosis, which is a clot in the veins of the brain. In 19 of these cases, doctors discovered, in addition to clots, a significant decrease in the number of platelets. With the exception of only two cases of a 36-year-old man and a 57-year-old man, the remaining cases were women between the ages of 20 and 63.

What is cerebral venous sinus thrombosis and what are its symptoms?

Experts of the German site Tageschau talk about a clot in the veins of the brain, which is responsible for transporting deoxygenated venous blood from the brain. Symptoms of cerebral venous sinus thrombosis include headache, epileptic seizures, and sometimes difficulty speaking.

The experts of the Institute, “Paul Ehrlich,” the aforementioned, that cases of clotting in the veins of the brain may be accompanied by a decrease in the proportion of platelets responsible for clotting blood to prevent bleeding, which may lead to bleeding. Among the symptoms accompanying the appearance of a rash of blood on the skin or mucous membranes or nosebleeds.

Is there a direct relationship between venous thrombosis cases in the brain and the AstraZeneca vaccine?

After the emergence of cases of cerebral venous sinus thrombosis, experts of the European Medicines Agency (EMA) confirmed that AstraZeneca vaccine is safe and effective. Experts did not confirm the existence of a direct relationship between cases of cerebral venous sinus thrombosis and the AstraZeneca vaccine, but at the same time they did not rule out the possibility of a relationship.

What is the cause of cerebral venous sinus thrombosis?

After examining blood samples from people with these conditions, doctors from the University of Greifsfield, Germany, reported that they found the reason for the clots occurring after receiving the AstraZeneca vaccine. In this context, Professor Andreas Grenacher, head of the transfusion unit at the Medical University of Greifsfield, says that the research conducted on the cases that could be examined, led to a repeated result.

He expresses his belief that taking the vaccine would activate the defensive reaction in the platelets, which caused the formation of clots in the brain. Usually, the body performs this reaction if the blood vessels are injured to stop the bleeding.

Research is still not completed to find out whether this is due to the vaccine itself or to the surrounding bacterial carrier, or whether this is related to general infections in the recipient’s body. To find out the cause of this reaction from the body, more tests must be performed.

What is the relationship of age to cerebral venous sinus thrombosis?

The committee of experts responsible for monitoring vaccines in Germany initially advised excluding those over 65 from receiving the AstraZeneca vaccine because the manufacturer did not provide results of research conducted on people of this age group. Then the expert committee corrected the situation and allowed people over the age of 18 to receive the vaccine.

And after the recent cases of cerebral venous sinus thrombosis, the committee reverted to recommending the AstraZeneca vaccine only to those over the age of sixty.

We must point out that those who have received the vaccine so far have received it either because of their age or their jobs, such as those working in the health or educational sector. According to the instructions provided by the Committee of Vaccine Experts, the authorities resorted to giving the elderly the Biontec-Pfizer vaccine, while the young people received the AstraZeneca vaccine.

How will those who received the first dose of the AstraZeneca vaccine be treated?

Experts stress that it is not expected that any complications will occur in those who received the first dose more than 16 days ago. Otherwise, those who feel symptoms for more than four days should see a doctor to find out the cause. Among the symptoms that need to see a doctor if they appear and last more than four days: headache and the appearance of a haematous granular rash on the skin.

And with the fact that The vaccine with AstraZeneca is given in two dosesWhat are the recommendations for those who receive a single dose? So far, the German Ministry of Health has not released any information about them and whether they can take another vaccine following the recent announcement. But experts believe that receiving more than one type of vaccine does not pose any danger to the person in theory, noting that there is no research in this context.

ABN / ANG





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