The Argentine said in a press conference today, Friday: “Mbabi felt pain in the calf muscle in his right leg.”
And he continued, “We hope he returns quickly.”
Paris hopes to catch up with Mbappe, 22, in the Champions League semi-final second leg on Tuesday against his host Manchester City.
It is a match in which Paris needs to score twice after losing 2-1 at home.
Paris will host the Lens team in the 35th round of the French League on Saturday.
Paris is ranked first, one point behind leaders Lille.