Galata Saray raised his score to the 75th point in second place in the Turkish league table, 6 points ahead of leaders Besiktas.
Two points behind Fenerbahce, who is third-placed, who has less matches left than Galatasaray and competes with him for second place.
Galatasaray striker Mostafa Mohamed and the Egyptian national team started the match on the bench.
While the dual attack was led by Rayan Babel and Khalil Darwish.
Galatasaray took the lead in the 44th minute through Khalil Darwish, and the first half ended with the visitors leading with a goal without a response.
In the second half, striker Emre Akababa added the second goal in the 53rd minute.
Akababa then added his second and third goal to Galata Saray in the 65th minute, before the referee decided to cancel the goal after returning to the video.
After the second goal, Galatasaray coach Fateh Terim pushed several changes, most notably the departure of Khalil Darwish and the participation of Radamel Falcao.
Arda Turan also participated instead of Ryan Babel.
In the 84th minute, Mostafa Mohamed participated in the second goal, replacing Emre Akababa.
Galatasaray has three matches left in the Turkish league against Besiktas, Denizlispor and Malataya Sport.
Mustafa Muhammad scored 6 goals for Galatasaray in 14 matches in the League and Turkey Cup.