Daily Mail: Scientists at the University of Nottingham are developing a universal vaccine for the Corona virus for all strains

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The British newspaper, “Daily Mail”, revealed that scientists at the University of Nottingham in England and a company Scancell Britain, they are developing a universal coronavirus vaccine that, in addition to surface mutants, targets a protein at the heart of the virus that is much less likely to mutate..

Scientists are developing a new vaccine for the Corona virus
Scientists are developing a new vaccine for the Corona virus

The newspaper said that human trials are expected to begin this year after positive results in mice showed that the vaccine can stimulate an immune response, and biotechnology companies in Belgium and France are working on similar methods.

The newspaper pointed out that scientists are currently conducting experiments to find a vaccine that protects against all strains of Corona, which they call the universal vaccine, to fight any strain of the Corona virus.

And the newspaper said, that a single blow that would provide protection against all variants of Corona could be a solution, experts say, as the world is “prepared” for epidemics.

The newspaper pointed out that the outbreak of any family of the coronavirus family is “inevitable”, due to the confluence of environmental and lifestyle factors such as fast travel and large cities, says Ted Schenkelberg, co-founder of the Human Vaccine Project, an international research organization based in New York, warning, saying: We live in a world ripe for epidemics“.

universal vaccine
universal vaccine

The newspaper pointed out that with 198 million cases of infection with the virus Corona Worldwide and more than 4.2 million deaths (with 5.88 million cases and around 130,000 deaths in the UK), no one wants a repeat of the last outbreak or worse..

The newspaper confirmed, SARS and Middle East Respiratory Syndrome were less contagious than Corona, but much more deadly, “the latter killed a third of the infected,” and the fear of a future strain that could combine the ease of transmission of Corona and deaths.

The newspaper added, a single global vaccine for the Corona virus is important, adding, we are still working to obtain the appropriate vaccine for the Corona virus, and the new strains of it that appear, regardless of the entire family of Corona viruses.

Earlier this year, the Coalition for Epidemic Preparedness Innovations launched (CEPI) , a global partnership to develop vaccines against infectious diseases, is a five-year £2.5 billion plan to “reduce or even eliminate the risk of future epidemics.”“.

The new campaign includes a £24 million partnership withVBI Vaccines , an American company, to develop a strike against all variants of Corona, including South African and Brazilian strains that are believed to be more transmissible and lethal.

The newspaper pointed out that the Coalition for Epidemic Preparedness Innovations CEPI, which has received £276m in funding from the UK government, is also seeking proposals from researchers working on ‘all-in-one’ vaccines that could protect against a wide range of coronaviruses including SARS and MERS.

Dr Richard Hatchett, CEO of the Coalition for Epidemic Preparedness Innovations, says: CEPI“It is unlikely that the coronavirus will be the last of the coronaviruses “.

“We know from history that other coronaviruses will almost certainly pass from animals to humans again and cause disease,” says Ted Schenkelberg, who has a background in infectious diseases and has worked in HIV vaccine programs. , or SARS X – And what will it be?.

And he said, the idea of ​​a universal vaccine is that it will work through any of the known coronaviruses, or any other vaccine lurking in animal warehouses, adding that, ideally, we want to be in a situation where we have stored vaccines before an outbreak of any new strain occurs.

Even better, he explained, people should already be vaccinated so that they are protected before the next pandemic, adding that to create a universal vaccine, scientists must focus on the common characteristics and structures of coronaviruses and then “exploit them.”“.

One approach being investigated is to target the way coronaviruses gain entry into the cell, and the target of existing vaccines.

Ted Schenkelberg, who has a background in infectious diseases and has worked on HIV vaccine programmes, said computer modeling and artificial intelligence could significantly speed up the process of identifying other structural “vulnerabilities”..

He told the newspaper Good Health: “We can use science to understand which coronaviruses will be a threat to humans, as well as the most protective immune responses, helping scientists design vaccines that protect against new threats.“.

Dr Chris Smith, a consultant virologist and lecturer at the University of Cambridge, said we should look for a universal vaccine for the Corona virus, but this does not mean that it will be easy to develop it, explaining that viruses hide the parts of the virus that do not change much between different strains to protect themselves and protect them effectively. And that makes it more difficult for them to exploit their vulnerabilities, so while I believe in the power of science, these viruses are hard to crack and sometimes it’s easier, cheaper, safer and faster to update our vaccines regularly, as we do with influenza. “.

And he said, that vaccines are not our only option, as Schinkelberg explains: “We can do things differently to reduce the chance of another epidemic, we need better management of the environment and monitoring of viruses in animals, so that we know what Corona viruses are spreading, we cannot go into 2020 again.” other.

And he wonders, but could the solution be a universal vaccine – a one-shot that provides protection against the coronavirus, all its forms, and all members of the coronavirus family?

He explained that the Corona virus is the third virus transmitted from animals to humans in the past two decades.

In 2002, SARS (Severe Acute Respiratory Syndrome) appeared in China, infecting more than 8,000 people and killing 774, and then, in 2012, the MERS virus appeared. MERS (Middle East Respiratory Syndrome) in Saudi Arabia, killing 881 people worldwide.



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